Spinach & Artichoke Chicken Bake

Featured in: Weeknight Dinners

This creamy spinach and artichoke chicken bake combines tender, seasoned chicken breasts with a tangy Greek yogurt-based topping featuring fresh spinach, artichoke hearts, and a blend of mozzarella and Parmesan cheeses. The dish comes together in just 45 minutes and delivers comforting, restaurant-quality results at home.

Simply season your chicken, sauté fresh spinach and garlic, then mix with Greek yogurt, artichokes, and cheese to create a luscious topping. Spread over the chicken and bake until golden and bubbly—the result is moist, flavorful protein that pairs beautifully with rice, quinoa, or a crisp salad.

Updated on Tue, 20 Jan 2026 08:28:00 GMT
Golden-brown Spinach & Artichoke Chicken Bake emerges from the oven with a bubbly, creamy topping of wilted greens and tender artichoke hearts.  Pin it
Golden-brown Spinach & Artichoke Chicken Bake emerges from the oven with a bubbly, creamy topping of wilted greens and tender artichoke hearts. | purposepan.com

The smell of bubbling cheese and garlic always pulls my husband into the kitchen before dinner is even close to ready. This chicken bake started on a chaotic Tuesday when I craving spinach artichoke dip but needed actual protein for dinner. Now it is the dish my kids actually ask for by name, which feels like a parenting win.

I first made this for a friend who was recovering from surgery and needed comforting food that was not heavy. She texted me three days later asking for the recipe because her husband had already requested it again. There is something about the tangy artichokes cutting through the rich yogurt that makes every bite interesting.

Ingredients

  • Boneless skinless chicken breasts: Pound them to even thickness so they cook at the same rate
  • Kosher salt and black pepper: Simple seasoning that lets the topping shine
  • Olive oil: Just enough to sauté the garlic and spinach
  • Fresh baby spinach: Wilts down quickly and adds beautiful green color
  • Canned artichoke hearts: Look for ones packed in water not oil for better texture
  • Garlic: Fresh minced makes all the difference here
  • Plain Greek yogurt: Whole milk yogurt gives the best creamy texture
  • Mozzarella and Parmesan cheese: The mozzarella melts while Parmesan adds salty depth
  • Dried oregano: Brings a subtle Italian herb flavor
  • Crushed red pepper flakes: Optional but adds a lovely warmth

Instructions

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Get the oven ready:
Preheat to 400°F and lightly grease a 9x13 baking dish
Season the chicken:
Sprinkle both sides with salt and pepper then arrange in the dish
Sauté the aromatics:
Heat olive oil in a skillet and cook garlic for 30 seconds then add spinach until wilted
Make the topping:
Mix the wilted spinach with artichokes yogurt cheeses and spices in a bowl
Top and bake:
Spread the mixture over chicken and bake 25 to 30 minutes until chicken reaches 165°F
Rest before serving:
Let the dish sit for 5 minutes so the juices redistribute
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Slice through the juicy, baked chicken breasts covered in a tangy, cheesy spinach and artichoke yogurt blend.  Pin it
Slice through the juicy, baked chicken breasts covered in a tangy, cheesy spinach and artichoke yogurt blend. | purposepan.com

This recipe became a regular when I realized my pickiest eater would happily eat spinach if it was covered in enough cheese. Now it is my go to when I want something that feels indulgent but is actually pretty healthy.

Making It Your Own

Sometimes I swap half the Greek yogurt for cream cheese when I want an extra rich version. Adding sun dried tomatoes or sautéed mushrooms turns this into a completely different meal that works just as well.

What To Serve With It

A simple green salad with vinaigrette cuts through the richness nicely. Rice or quinoa soaks up the extra sauce but roasted vegetables work just as well for a lighter meal.

Storage And Reheating

Leftovers keep well in the refrigerator for up to three days. Reheat gently in the microwave with a splash of water to keep the topping from drying out.

  • Freeze individual portions for quick weeknight lunches
  • The topping may separate slightly after freezing but still tastes great
  • Always reheat to 165°F for food safety
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A close-up of a serving of Spinach & Artichoke Chicken Bake on a plate, garnished with fresh herbs and ready for a weeknight dinner. Pin it
A close-up of a serving of Spinach & Artichoke Chicken Bake on a plate, garnished with fresh herbs and ready for a weeknight dinner. | purposepan.com

There is nothing quite like pulling this bubbling dish out of the oven and watching everyone hurry to the table.

Recipe FAQs

Can I prepare this dish in advance?

Yes, you can assemble the entire dish up to 24 hours ahead. Cover and refrigerate, then bake when ready. Add a few extra minutes to cooking time if baking from cold.

What can I substitute for Greek yogurt?

Light cream cheese, sour cream, or a combination of mayonnaise and Greek yogurt work well. For a lighter option, try plain yogurt mixed with a bit of cream cheese for richness.

How do I know when the chicken is cooked through?

Use an instant-read thermometer to check that the thickest part of the chicken reaches 165°F (74°C). The meat should be opaque throughout with no pink inside.

Can I use frozen spinach instead of fresh?

Absolutely. Use 1 cup of thawed, well-drained frozen spinach. Squeeze out excess moisture to prevent the topping from becoming watery.

What are good serving suggestions?

Serve alongside fluffy rice, creamy mashed potatoes, or nutty quinoa. A crisp green salad or roasted vegetables like broccoli or Brussels sprouts complement the rich topping perfectly.

How should I store leftovers?

Store in an airtight container in the refrigerator for up to 3 days. Reheat gently in a 350°F oven for about 10-12 minutes or microwave individual portions until warmed through.

Spinach & Artichoke Chicken Bake

Tender chicken breasts baked under a creamy spinach and artichoke topping with Greek yogurt and cheese.

Prep time
15 minutes
Cook time
30 minutes
Total duration
45 minutes
Author Amelia Cook


Skill Level Easy

Cuisine American

Portions 4 Serving size

Diet Information No Gluten, Low Carb

What You Need

Chicken

01 4 boneless, skinless chicken breasts (about 1.5 lbs)
02 1/2 teaspoon kosher salt
03 1/4 teaspoon freshly ground black pepper

Spinach & Artichoke Topping

01 1 tablespoon olive oil
02 2 cups fresh baby spinach, roughly chopped
03 1 (14 oz) can artichoke hearts, drained and coarsely chopped
04 2 cloves garlic, minced
05 1 cup plain Greek yogurt, whole milk
06 1/2 cup shredded mozzarella cheese
07 1/4 cup grated Parmesan cheese
08 1/4 teaspoon dried oregano
09 1/4 teaspoon crushed red pepper flakes, optional

Step-by-Step Guide

Step 01

Prepare Baking Dish and Chicken: Preheat oven to 400°F. Lightly grease a 9x13-inch baking dish. Season chicken breasts with salt and pepper, then arrange in a single layer in the prepared dish.

Step 02

Sauté Aromatics and Spinach: Heat olive oil in a skillet over medium heat. Add minced garlic and sauté for 30 seconds until fragrant. Add chopped spinach and cook until just wilted, approximately 2 minutes.

Step 03

Combine Topping Mixture: In a mixing bowl, combine sautéed spinach, chopped artichoke hearts, Greek yogurt, mozzarella cheese, Parmesan cheese, oregano, and red pepper flakes. Mix until well combined.

Step 04

Apply Topping: Spread the spinach and artichoke mixture evenly over the chicken breasts, covering completely.

Step 05

Bake Until Cooked Through: Bake for 25 to 30 minutes, until chicken reaches an internal temperature of 165°F and the topping is golden and bubbly.

Step 06

Rest and Serve: Remove from oven and let rest for 5 minutes before serving.

What You'll Need

  • 9x13-inch baking dish
  • Skillet
  • Mixing bowl
  • Knife and chopping board
  • Measuring cups and spoons

Allergy List

Review all items for allergens and talk to a medical expert if you're unsure.
  • Contains dairy: Greek yogurt, mozzarella, and Parmesan cheese
  • May contain eggs if using egg-enriched cheese varieties
  • Gluten-free as written; verify product labels for potential cross-contamination if sensitive

Nutrition details (per portion)

Nutrition details are just for your reference and shouldn't substitute a medical consultation.
  • Calories: 325
  • Fat content: 11 grams
  • Carbohydrates: 7 grams
  • Protein: 48 grams